Methods and reagents for diagnosis of autoantibodies

Details Methods and reagents for diagnosis of autoantibodies Methods and reagents for diagnosis of autoantibodies

C - Chemistry, Metallurgy

07

K

C07K 14/435 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 39/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) G01N 33/564 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2117904

A number of octapeptides were generated from the sequences encoding the 60 kDa Ro/SSA peptide, the La/SSB autoantigen, the 70 kD nuclear ribonucleoprotein (nRNP), and the Sm B/B' polypeptide, which represent linear epitopes for autoantibodies present in the sera of SLE and SS patients. These peptides are useful in solid phase assays for patients characterized by the presence of these autoantibodies, and can be used to categorize patients as to the likelihood of developing certain conditions associated with SLE. The peptides are also potentially useful in treatment of these patients using immobilized peptide to remove autoantibody and to block binding of the autoantibodies with patient molecules reactive with the autoantibodies.

Affiliated with

Also associated with

Rating

Methods and reagents for diagnosis of autoantibodies does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and reagents for diagnosis of autoantibodies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and reagents for diagnosis of autoantibodies will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2006001