Asymmetric hydrogenation of furoimidazole derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 491/048 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2134441

2134441 9424137 PCTABS00034 A process for the asymmetric hydrogenation of furoimidazole derivatives of general formula (I) with hydrogen in the presence of a homogeneous catalyst to give the corresponding diastereomeric dihydrofuroimidazole derivatives of general formula (II). The dihydrofuroimidazole derivatives of general formula (II) are intermediates for the preparation of (+)-biotin.

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