Long-wavelength fps

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07K 14/435 (2006.01) C08L 89/00 (2006.01) C12N 1/20 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12Q 1/04 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2536645

Two long-wavelength flourescent proteins isolated from the strawberry anemone, Corynactis californica are provided. These proteins are homologous to known fluorescent proteins, but their unique properties, including yellow or red color of emission, can find use in replacing and supplementing known fluorescent proteins. In addition because of their longer wavelength absorption and emission spectra, they can be used in energy transfer applications with the known shorter wavelenght fluorescent proteins and non- proteinaceous fluorescers.

L'invention concerne deux protéines fluorescentes de grande longueur d'onde isolées de l'anémone corallienne rouge, Corynactis californica. Ces protéines sont homologues à des protéines fluorescentes connues mais, grâce à leurs propriétés uniques parmi lesquelles figurent la couleur d'émission jaune ou rouge, ces protéines peuvent venir remplacer ou compléter des protéines fluorescentes connues. De plus, grâce à leur spectre d'émission et d'absorption de plus grande longueur d'onde, ces protéines peuvent être utilisées dans des applications de transfert d'énergie avec les agents de fluorescence non protéiques et protéines fluorescentes de plus petite longueur d'onde connus.

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