Antibodies against gpi.alpha.

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/16 (2006.01) C12N 5/078 (2010.01) A61K 39/395 (2006.01) A61P 7/02 (2006.01) C07K 16/28 (2006.01) C07K 17/00 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2689726

This application relates to agents capable of specifically recognizing GPIb.alpha., a key receptor required for platelet adhesion and aggregation. More specifically, this application relates to monoclonal antibodies and derivatives thereof capable of specifically recognizing both the murine and the human GPIb.alpha.. These monoclonal antibodies and derivatives are particularly useful in the treatment or prevention of thrombosis as well as research tools.

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