Scorpion toxins

Details Scorpion toxins Scorpion toxins

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01N 63/02 (2006.01) C07K 14/435 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12N 15/82 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2341062

This invention relates to an isolated nucleic acid fragment encoding a scorpion sodium channel agonist. The invention also relates to the construction of a chimeric gene encoding all or a portion of the scorpion sodium channel agonist, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the scorpion sodium channel agonist in a transformed host cell.

L'invention se rapporte à un fragment d'acide nucléique isolé codant pour un agoniste des canaux sodiques du scorpion. Elle se rapporte également à la construction d'une gène chimère codant pour tout ou partie de l'agoniste des canaux sodiques du scorpion, selon une orientation sens ou antisens, construction au cours de laquelle l'expression du gène chimère se traduit par la production de taux modifiés de l'agoniste des canaux sodiques du scorpion dans une cellule hôte transformée.

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