Methods and compositions using...

A - Human Necessities – 61 – K

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A61K 31/454 (2006.01) A61K 31/573 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2476983

Methods of treating, preventing and/or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone or in combination with a second active ingredient. The invention further relates to methods of reducing or avoiding adverse side effects associated with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy which comprise the administration of an immunomodulatory compound. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.

La présente invention se rapporte à des méthodes de traitement, prévention et/ou prise en charge du cancer et d'autres maladies et troubles associés à une angiogenèse indésirable ou caractérisés par une telle angiogenèse. Des méthodes spécifiques incluent l'administration d'un composé immunomodulateur seul ou en association à un second ingrédient actif. L'invention se rapporte également à des méthodes permettant de réduire ou de supprimer les effets secondaires néfastes associés à la chimiothérapie, à la radiothérapie, à la thérapie hormonale, à la thérapie biologique ou à l'immunothérapie, qui consistent en l'administration d'un composé immunomodulateur. L'invention se rapporte également à des compositions pharmaceutiques, à des formes posologiques monodoses ainsi qu'à des trousses adaptées à la mise en oeuvre des méthodes de la présente invention.

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