Inhibitors of type 5 and type 3 17.beta.-hydroxysteroid...

C - Chemistry – Metallurgy – 07 – J

Patent

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C07J 63/00 (2006.01) A61K 31/566 (2006.01) A61K 31/5685 (2006.01) A61K 31/57 (2006.01) A61K 31/58 (2006.01) A61K 31/585 (2006.01) A61K 45/06 (2006.01) A61P 13/08 (2006.01) A61P 17/00 (2006.01) C07J 1/00 (2006.01) C07J 7/00 (2006.01) C07J 21/00 (2006.01) C07J 31/00 (2006.01) C07J 41/00 (2006.01)

Patent

CA 2323089

Novel methods of medical treatment and/or inhibition of development of diseases are disclosed for diseases that are sensitive to androgenic or estrogenic activity. The treatments utilize inhibitors of type 5 and/or type 3 17.beta.-hydroxysteroid dehydrogenase. Novel inhibitors of type 5 17.beta.- hydroxysteroid dehydrogenase are also disclosed, as are novel inhibitors of type 3 17.beta.-hydroxysteroid dehydrogenase.

L'invention concerne de nouvelles méthodes de traitement médical et/ou d'inhibition du développement de maladies, lesquelles méthodes concernent des maladies sensibles à l'activité androgène et oestrogène. Lesdits traitements font appel à des inhibiteurs de la 17.beta.-hydroxystéroïde déshydrogénase du type 5 et/ou du type 3. L'invention concerne également de nouveaux inhibiteurs de la 17.beta.-hydroxystéroïde déshydrogénase du type 5 et de nouveaux inhibiteurs de la 17.beta.-hydroxystéroïde déshydrogénase du type 3.

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