C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 213/08 (2006.01) C07C 213/02 (2006.01) C07C 231/14 (2006.01) C07C 233/05 (2006.01) C07D 307/20 (2006.01) C07D 317/12 (2006.01) C07D 317/28 (2006.01) C07C 215/40 (2006.01)
Patent
CA 2333199
A process for the preparation of protected dihydroxypropyl trialkylammonium salts, particularly in chiral form is described. In particular, a process for the preparation of (2,2-dimethyl-1,3-dioxolan-4- ylmethyl) trialkylammonium salts, particularly in chiral form is described. Furthermore, a process is described wherein the (2,2- dimethyl-1,3-dioxolan-4ylmethyl) trialkylammonium salts is a 2,2-dimethyl-1,3-dioxolan-4-ylmethyl trimethylammonium salt, preferably in chiral form. The protected dihydroxypropyl trialkylammonium salts lead to L-carnitine (9) when in chiral form (5).
L'invention porte sur un procédé de préparation de sels protégés de dihydroxypropyltrialkylammonium en particulier sous la forme chirale. L'invention porte notamment: sur un procédé de préparation dans lequel le (2,2-diméthyl-1,3-dioxolan-4-ylméthyl) trialkylammonium est un (2,2-diméthyl-1,3-dioxolan-4-ylméthyl) triméthylammonium de préférence sous la forme chirale. Les sels protégés de dihydroxypropyl trialkylammonium sous la forme chirale (5) conduisent à la L-carnitine (9).
Hollingsworth Rawle I.
Wang Guijun
Macrae & Co.
Michigan State University
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