C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 235/00 (2006.01) C07C 259/06 (2006.01) C07C 271/22 (2006.01) C07C 311/06 (2006.01) C07C 311/08 (2006.01) C07C 311/16 (2006.01) C07C 311/21 (2006.01) C07D 257/04 (2006.01) C07D 295/155 (2006.01) C07D 295/205 (2006.01) C07D 307/79 (2006.01) C07D 317/60 (2006.01) C07D 413/04 (2006.01)
Patent
CA 2301038
This invention relates to molecules which inhibit metalloproteinases such as formulas (I, IV) including aggrecanase, and the production of tumor necrosis factor (TNF). In particular, the compounds are inhibitors of metalloproteinases involved in tissue degradation and inhibitors of the release of tumor necrosis factor. The present invention also relates to pharmaceutical compositions comprising such compounds and to methods of using these compounds for the treatment of inflammatory diseases.
L'invention concerne des molécules qui inhibent les métalloprotéinases, y compris l'aggrécanase, ainsi que la production de facteur de nécrose tumoral. En particulier, les composés selon l'invention sont des inhibiteurs des métalloprotéinases, impliqués dans la dégradation tissulaire et des inhibiteurs de la libération du facteur de nécrose tumoral. La présente invention traite également de compositions pharmaceutiques comprenant ces composés, et de procédés mettant en oeuvre ces composés pour traiter les maladies inflammatoires.
Decicco Carl P.
Yao Wenqing
Bristol-Myers Squibb Pharma Company
Dimock Stratton Llp
Dupont Pharmaceuticals Company
LandOfFree
Novel inhibitors of aggrecanase and matrix... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel inhibitors of aggrecanase and matrix..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel inhibitors of aggrecanase and matrix... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2010428