C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/00 (2006.01) C12N 9/48 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2044595
2044595 9008457 PCTABS00001 The invention discloses the amino acid sequence of Acyl-Peptide Hydrolase. The invention relates to a DNA molecule encoded for Acyl-Peptide Hydrolase, a vector incorporating the molecule, and the use of such vector to transform a host. The invention further relates to the expression by the host to produce Acyl-Peptide Hydrolase, and the use of APH to catalyze the hydrolysis of an N.alpha.-acetylated peptide or protein or the reaction between a N.alpha.-acetyl amino acid donor and an acceptor protein with a free .alpha.-NH2 group. The invention further relates to the use of the Acyl-Peptide Hydrolase-encoding sequences in the detection of cancer.
Gowling Lafleur Henderson Llp
The General Hospital Corporation
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