Methods for treating autoimmune diseases in a subject and in...

A - Human Necessities – 61 – K

Patent

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A61K 39/38 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 38/21 (2006.01) A61K 38/40 (2006.01) A61K 39/00 (2006.01) A61K 39/42 (2006.01) C07K 16/22 (2006.01) C07K 16/24 (2006.01) G01N 33/564 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2433806

The invention provides a method for treating an autoimmune disease in a subject by administering an interferon antagonist and a Flt3 ligand (Flt3L) antagonist. The invention also provides compositions containing one or more interferon antagonists, and one or more Flt3L antagonists, an in vitro assay for determining a subject's risk for developing an autoimmune disease, and kits for use, inter alia, with the assay.

L'invention concerne un traitement de maladie auto-immune chez un sujet par l'administration d'un agoniste d'interféron et d'un antagoniste de ligand Flt3 (Flt3L). L'invention concerne aussi des compositions contenant un ou plusieurs antagonistes d'interféron, et un ou plusieurs antagonistes Flt3L, une technique <i>in vitro</i> permettant de déterminer le risque que présente un sujet de développer une maladie auto-immune, ainsi que des trousses s'utilisant entre autres dans cette technique.

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