Angiotensin ii receptor blocking quinazolones

Details Angiotensin ii receptor blocking quinazolones Angiotensin ii receptor blocking quinazolones

C - Chemistry, Metallurgy

07

D

C07D 403/10 (2006.01) C07D 239/88 (2006.01) C07D 239/90 (2006.01) C07D 239/91 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07F 7/08 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2060154

31,559 ANGIOTENSIN II RECEPTOR BLOCKING 2,3,6 SUBSTITUTED QUINAZOLINONES ABSTRACT Novel quinazolinone compounds of the formula: Image wherein R5, R6, R7, R8, R and X are defined in the specification, which have angiotensin II (AII) antago- nizing activity, intermediates useful in the prepara- tion of the compounds, methods of producing and using the compounds to alleviate angiotensin induced hyper- tension and treat congestive heart failure in mammals.

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