Blocking expression of virulence factors in s. aureus

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/31 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2256465

This invention provides peptides which inhibit agr transcription in S. aureus and thereby block the expression of virulence factors in S. aureus, pharmaceutical compositions comprising these peptides, as well as methods for treating or preventing an infection or disease caused by S. aureus using the peptides of the present invention.

L'invention décrit des peptides qui inhibent la transcription agr dans S. aureus et, de ce fait, bloque l'expression de l'aggressine dans S. aureus, des compositions pharmaceutiques comprenant lesdits peptides ainsi que des procédés utilisant les peptides de la présente invention pour le traitement ou la prévention d'une infection ou d'une maladie causée par S. aureus.

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