Halogenated benzamide derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 277/46 (2006.01) A61K 31/426 (2006.01)

Patent

CA 2580347

A halogenated benzamide derivative characterized by greater specificity for viral pathogens and less disruptive to beneficial gut microflora, according to formula (III): in which R1 is a halogen atom, and R2 -R6 are independently hydrogen, hydroxyl, C1 -C4 alkyl, -C1-C4 alkoxy, acyloxy, nitro, halogen, - C(O)R7 where R7 is -C1-C4 alkyl, or aromatic including salts and hydrates of these compounds.

L'invention concerne un dérivé de benzamide halogéné se caractérisant par une plus grande spécificité pour des agents pathogènes viraux et moins perturbateur pour la microflore intestinale bénéfique, selon la formule (III), dans laquelle R1 représente un atome d'halogène, et R2 R6 représentent indépendamment hydrogène, hydroxyle, C1-C4 alkyle, C1-C4 alcoxy, acyloxy, nitro, halogène, -C (O) R7, R7 représentant C1-C4 alkyle ou un aromatique renfermant des sels et des hydrates de ces composés.

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