A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/00 (2006.01) A61K 31/155 (2006.01) A61K 31/167 (2006.01) A61K 31/192 (2006.01) A61K 31/405 (2006.01) A61K 31/438 (2006.01) A61K 31/439 (2006.01) A61K 31/444 (2006.01) A61K 31/465 (2006.01) A61K 31/616 (2006.01) A61K 45/06 (2006.01) A61P 1/00 (2006.01)
Patent
CA 2571584
A method of treating ileus in a subject by administering to the subject an effective amount of a pharmacological agent that increases the activity of cholinergic receptor in a subject. Examples of pharmacological agents are brain muscarinic agonist, cholinergic agonist or cholinesterase inhibitor. The methods of the present invention can be used to treat ileus caused by abdominal surgery, or administration of narcotics or chemotherapeutic agents such as during cancer chemotherapy.
L'invention concerne une méthode pour traiter une occlusion intestinale chez un sujet comprenant l'administration d'une quantité efficace d'un agent pharmacologique qui améliore l'activité du récepteur cholinergique chez un sujet. Des exemples d'agents pharmacologiques sont un antagoniste muscarinique du cerveau, un agoniste chloinergique ou un inhibiteur de cholinestérase. Les méthodes de l'invention peuvent être utilisées pour traiter une occlusion intestinale provoquée par une opération de l'abdomen, ou par l'administration d'agents narcotique ou chimiothérapeutiques, dans le cas d'une chimiothérapie contre le cancer.
Fink Mitchell P.
Tracey Kevin J.
Gowling Lafleur Henderson Llp
The Feinstein Institute For Medical Research
University Of Pittsburgh - Of The Commonwealth System Of Higher
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