C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 217/08 (2006.01) A61K 31/4035 (2006.01) A61K 31/4709 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07D 209/44 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/04 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2623879
The present invention is related to sulfonamide derivatives of Formula (Ia) where the groups are as defined in the description, and use thereof in particular for the treatment and/or prophylaxis of autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, cancer, respiratory diseases and fibrosis, including multiple sclerosis, arthritis, emphysema, chronic obstructive pulmonary disease, liver and pulmonary fibrosis.
La présente invention concerne des dérivés sulfonamide de formule (Ia) dont les groupes sont définis tels que dans la description, et leur utilisation en particulier pour le traitement et/ou la prophylaxie de troubles auto-immuns, maladies inflammatoires, maladies cardio-vasculaires, maladies neurodégénératives, cancers, maladies et fibrose respiratoires, y compris sclérose en plaques, arthrite, emphysème, maladie pulmonaire obstructive chronique, fibrose hépatique et pulmonaire.
Bombrun Agnes
Gerber Patrick
Swinnen Dominique
Kirby Eades Gale Baker
Laboratoires Serono S.a.
Merck Serono Sa
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