Human natural killer cell activating factor ii

Details Human natural killer cell activating factor ii Human natural killer cell activating factor ii

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 31/70 (2006.01) A61K 38/19 (2006.01) A61K 48/00 (2006.01) C07K 14/52 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2250269

The invention relates to NKAF II polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.

La présente invention a trait à des polypeptides, facteurs d'activation de cellules tueuses naturelles (NKAF II) chez l'homme, à des polynucléotides codant pour ces polypeptides et à des procédés de production de tels polypeptides, en particulier en exprimant les polynucléotides en question, ainsi qu'à des agonistes et antagonistes desdits polypeptides. L'invention concerne également des procédés d'utilisation de tels polynucléotides, polypeptides, agonistes et antagonistes pour certaines applications se rapportant, entre autres, à la recherche et aux techniques aussi bien diagnostiques que cliniques.

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