Transplantation of neural cells

Details Transplantation of neural cells Transplantation of neural cells

A - Human Necessities

61

F

A61F 2/06 (2006.01)

Patent

CA 2645186

Restoration or increase of inhibitory interneuron function in vivo is achieved by transplantation of MGE cells into the brain. Compositions containing MGE cells are provided as are uses to treat various diseases characterised by abnormal inhibitory interneuron function or in cases where increase inhibition may ameliorate neural circuits that are abnormally activated.

L'invention concerne la restauration ou l'augmentation de la fonction des interneurones inhibiteurs in vivo consistant à transplanter des cellules MGE dans le cerveau. L'invention concerne également des compositions renfermant des cellules MGE, ainsi que des utilisations de celles-ci à des fins de traitement de diverses maladies caractérisées par une fonction des interneurones inhibiteurs anormale ou dans des cas où l'inhibition de l'augmentation pourrait améliorer des circuits neuraux qui sont activés de manière anormale.

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