C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 21/08 (2006.01) C07K 16/00 (2006.01) C07K 16/08 (2006.01) C07K 16/10 (2006.01) C07K 16/28 (2006.01) C12N 5/16 (2006.01)
Patent
CA 2056102
The invention relates to a novel method for the generation of monoclonal antibodies. The method involves the combination of a clonal expansion of B-lymphocytes followed by or preceded by a selection of B-lymphocytes which produce antibodies with the desired specificity. The selected lymphocytes are immortalized. The invention makes it possible to use any source of B- lymphocytes no matter how small.
Akzo N.v.
Fetherstonhaugh & Co.
N.v. Organon
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