Method for the production of antibodies

C - Chemistry – Metallurgy – 12 – P

Patent

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Details

C12P 21/08 (2006.01) C07K 16/00 (2006.01) C07K 16/08 (2006.01) C07K 16/10 (2006.01) C07K 16/28 (2006.01) C12N 5/16 (2006.01)

Patent

CA 2056102

The invention relates to a novel method for the generation of monoclonal antibodies. The method involves the combination of a clonal expansion of B-lymphocytes followed by or preceded by a selection of B-lymphocytes which produce antibodies with the desired specificity. The selected lymphocytes are immortalized. The invention makes it possible to use any source of B- lymphocytes no matter how small.

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