Pyridinylpiperazin derivatives useful as modulators of...

Details Pyridinylpiperazin derivatives useful as modulators of... Pyridinylpiperazin derivatives useful as modulators of...

C - Chemistry, Metallurgy

07

D

C07D 213/74 (2006.01) A61K 31/444 (2006.01) A61P 25/30 (2006.01)

Patent

CA 2730002

The present invention relates to compounds of the general formula (I), having affinity and selectivity for the dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful for the therapeutic and/or prophylactic treatment of cognitive disorders.

La présente invention concerne des composés représentés par la formule générale (I), présentant une affinité et un sélectivité pour les récepteurs D3 de la dopamine, leur fabrication, des compositions pharmaceutiques les contenant ainsi que leur utilisation en tant que médicaments. Les composés actifs de la présente invention sont utiles pour le traitement thérapeutique et/ou prophylactique de troubles cognitifs.

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