C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 513/04 (2006.01) A61K 31/437 (2006.01) A61P 3/00 (2006.01) A61P 25/00 (2006.01) A61P 37/00 (2006.01)
Patent
CA 2696298
The present invention relates to modulators of ATP-Binding Cassette ('ABC') transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
L'invention porte sur des modulateurs des transporteurs à cassette de liaison à l'ATP ('ATP-Binding Cassette' ou ABC) ou des fragments de ces derniers, y compris le régulateur de la conductance transmembranaire de la fibrose kystique, sur des compositions desdits régulateurs et sur des procédés associés. L'invention concerne également des procédés qui permettent de traiter les maladies médiées par le transporteur ABC à l'aide des modulateurs précités.
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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