Azolobenzazepine derivatives as neurologically active agents

Details Azolobenzazepine derivatives as neurologically active agents Azolobenzazepine derivatives as neurologically active agents

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2247453

The invention relates to azolobenzazepine derivatives of formula (I), wherein: X is O or S; R1, R2, R3 and R4 are independently hydrogen, perfluorolower- alkyl, halogen, nitro or cyano; and C together with the carbon atoms to which it is attached forms a 5-membered aromatic heterocycle, to pharmaceutical compositions containing them and to methods for the treatment of neurological disorders utilizing them.

La présente invention concerne des dérivés d'azolobenzazépine représentés par la formule générale (I). Dans cette formule X est O ou S; R?1¿, R?2¿, R?3¿ et R?4¿ sont indépendamment hydrogène, perfluoro-alkyl inférieur, halogène, nitro ou cyano; et C avec les atomes de carbones avec lesquels il possède une liaison forme un hétérocycle aromatique à 5 segments. L'invention, qui concerne également des compositions pharmaceutiques contenant ces dérivés, concerne aussi une thérapie de ces troubles neurologiques utilisant de telles compositions.

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