Methods for detecting cells with numerical chromosomal...

Details Methods for detecting cells with numerical chromosomal... Methods for detecting cells with numerical chromosomal...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/554 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2413177

The invention provides methods for detecting mitotic cells having numerical chromosomal abnormalities and agents inducing numericalchromosomal abnormalities in cells. In a preferred embodiment, the method comprises staining a cell with a mitotic marker: that detects cells in mitosis, and a quantitative DNA stain, indicating the amount of DNA in the mitotic cell. Stained cells are preferably analyzed by flow cytometry.

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