A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/16 (2006.01) A61K 31/38 (2006.01) A61K 31/405 (2006.01)
Patent
CA 2643559
Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, and Pichinde), Filoviridae (Ebola and Marburg viruses), Flaviviridae (yellow fever, Omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever).
La présente invention concerne les composés, méthodes et compositions pharmaceutiques pour le traitement d'infections virales par l'administration de certains nouveaux composés en quantités thérapeutiques efficaces. L'invention porte également sur des méthodes de préparation des composés et des méthodes d'utilisation des composés et des compositions pharmaceutiques les contenant. L'invention concerne plus particulièrement le traitement et la prophylaxie d'infections virales telles que celles causées par les virus de la fièvre hémorragique, y compris mais s'en s'y limiter, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe et Pichinde), Filoviridae (virus Ebola et Marburg), Flaviviridae (virus de la fièvre jaune, de la fièvre hémorragique d'Omsk et de la maladie de la forêt de Kyasanur) et enfin Bunyaviridae (fièvre de la vallée du Rift).
Amberg Sean
Bolken Tove
Dai Dongcheng
Hruby Dennis E.
Dimock Stratton Llp
Siga Technologies Inc.
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