Synthetic senescent cell antigen

Details Synthetic senescent cell antigen Synthetic senescent cell antigen

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61M 1/38 (2006.01) B01D 15/08 (2006.01) B01D 53/04 (2006.01) C07K 4/12 (2006.01) C07K 14/075 (2006.01) C07K 14/705 (2006.01) C07K 17/00 (2006.01) G01N 33/564 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2083150

2083150 9118013 PCTABS00008 Disclosed herein is a synthetic senescent cell antigen comprised of purified peptides immunoreactive with antibodies to the naturally occurring antigen. Preferably, the synthetic senescent cell antigen comprises two peptides with the amino acid sequences SKLIKIFQDHPLQKTYN and LFKPPKYHPDVPYVKR, respectively. The antigen and peptides may be used in compositions, diagnostic kits, and methods for detecting or measuring antibodies to senescent cell antigen, studying cellular aging and autoimmune mechanisms, separating anions from a gas or liquid, or treating certain diseases.

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