Use of potent, selective and non toxic c-kit inhibitors for...

Details Use of potent, selective and non toxic c-kit inhibitors for... Use of potent, selective and non toxic c-kit inhibitors for...

A - Human Necessities

61

K

A61K 31/00 (2006.01) A61K 31/015 (2006.01) A61K 31/095 (2006.01) A61K 31/40 (2006.01) A61K 31/403 (2006.01) A61K 31/404 (2006.01) A61K 31/415 (2006.01) A61K 31/4709 (2006.01) A61K 31/498 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61K 31/66 (2006.01) A61K 45/06 (2006.01) A61P 13/10 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2460845

The present invention relates to a method for treating interstitial cystitis, comprising administering a tyrosine kinase inhibitor to a human in need of such treatment, more particularly a non-toxic, potent and selective c-kit inhibitor, wherein said inhibitor is unable to promote death of IL-3 dependent cells cultured in presence of IL-3.

L'invention concerne une méthode de traitement de la cystopathie interstitielle sous-muqueuse qui consiste à administrer un inhibiteur de tyrosine kinase à un être humain nécessitant ce traitement, et plus spécifiquement un inhibiteur de c-kit non toxique, puissant et sélectif. Cet inhibiteur ne peut pas favoriser la mort des cellules dépendantes de IL-3 cultivées en présence de IL-3.

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