Composition for improving cognition and memory

Details Composition for improving cognition and memory Composition for improving cognition and memory

A - Human Necessities

61

K

A61K 31/405 (2006.01)

Patent

CA 2521182

The invention relates to a pharmacologically active combination, having utility in treating insomnia patients, which comprises: (a) at least one first active ingredient selected from melatonin, other melatonergic agents, melatonin agonists and melatonin antagonists; and (b) at least one second active ingredient selected from nicotine and nicotine receptor agonists; to use of a medicament containing component (a) with or without component (b) for alleviation of at least one adverse effect which occurs in a patient in the course of nicotine replacement therapy, or otherwise, selected from impairment of the quality of sleep, impairment of cognition and impairment of memory, as well as to a kit having utility in treating insomnia patients, which comprises components (a) and (b) in unit dosage form.

L'invention concerne une combinaison active sur le plan pharmacologique, permettant de traiter des patients insomniaques, comprenant : (a) au moins un premier ingrédient actif sélectionné dans le groupe comprenant de la mélatonine, d'autres agents mélatonergiques, des agonistes de la mélatonine et des antagonistes de la mélatonine ; et (b) au moins un second ingrédient actif sélectionné dans le groupe comprenant de la nicotine et des agonistes du récepteur nicotinique. L'invention concerne également l'utilisation d'un médicament contenant le composant (a) avec ou sans le composant (b), permettant de traiter au moins un effet indésirable apparaissant chez un patient au cours d'une thérapie de substitution de la nicotine, ou, sinon, de traiter les troubles du sommeil, les troubles de la cognition et les troubles de la mémoire. L'invention concerne également un kit permettant de traiter les patients insomniaques, comprenant les composants (a) et (b) en doses unitaires.

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