C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 221/04 (2006.01) A61K 31/435 (2006.01) A61K 31/47 (2006.01) A61K 31/498 (2006.01) A61K 31/517 (2006.01) A61P 37/00 (2006.01) C07D 215/48 (2006.01) C07D 239/70 (2006.01) C07D 241/40 (2006.01)
Patent
CA 2568673
The present invention provides novel compounds of Formula I which are antagonists of the C5a receptor. Compounds of the present invention are useful for the treatment of various C5a-mediated diseases and disorders; accordingly the present invention provides a method for the treatment of C5a-mediated diseases using the novel compounds described herein, as well as pharmaceutical compositions containing them.
La prEsente invention concerne des nouveaux composEs de formule I qui sont des antagonistes du rEcepteur de la C5a. Les composEs de la prEsente invention sont utiles pour le traitement de diffErentes maladies et troubles mEdiEs par la C5a. Par consEquent, la prEsente invention se rapporte à un procEdE pour le traitement de maladies mEdiEes par la C5a, utilisant les nouveaux composEs dEcrits ici, ainsi que des compositions pharmaceutiques les contenant.
Lachance Nicolas
Leblanc Yves
Roy Patrick
Merck Frosst Canada Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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