Recombinant .alpha.-n-acetylgalactosaminidase enzyme and...

Details Recombinant .alpha.-n-acetylgalactosaminidase enzyme and... Recombinant .alpha.-n-acetylgalactosaminidase enzyme and...

C - Chemistry, Metallurgy

12

N

C12N 15/56 (2006.01) A61K 35/18 (2006.01) C12N 5/10 (2006.01) C12N 9/24 (2006.01) C12S 3/22 (2006.01)

Patent

CA 2159083

This invention relates to a recombinant enzyme for use in the removal of A antigens from the surface of cells in blood products. Specifically, this invention is directed to a recombinant .alpha.-N- acetylgalactosaminidase enzyme from chicken liver, methods of cloning and expressing said recombinant .alpha.-N-acetylgalactosaminidase enzyme and a method of removing A antigens from the surface of cells in blood products using said recombinant .alpha.-N-acetylgalactosaminidase enzyme.

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