Plasma retention structure providing internal flow

Details Plasma retention structure providing internal flow Plasma retention structure providing internal flow

G - Physics

01

N

G01N 33/49 (2006.01) A61K 35/14 (2006.01) B01L 3/00 (2006.01) G01N 21/00 (2006.01)

Patent

CA 2331855

A capillary hematocrit separation structure is included within a housing having a fluid inlet port, a reaction region, and a capillary pathway connecting the inlet port and the reaction region. The capillary pathway is dimensioned so that the driving force for the movement of liquid through the capillary pathway arises from capillary pressure. A plurality of obstructions are fixed in the capillary pathway, each obstruction having a concave portion facing toward the vented reaction region on the down stream side of the obstructions as viewed with reference to a liquid flowing from the inlet port to the reaction region. The capillary pathway in a hematocrit separation structure for a single drop sample size includes about 10 5 obstructions, each obstruction including a concave portion having a volume of between about 10-4 to 10-5 µl for selectively receiving hematocrit.

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