Thioformamide derivatives

Details Thioformamide derivatives Thioformamide derivatives

C - Chemistry, Metallurgy

07

D

C07D 213/59 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07C 327/46 (2006.01) C07D 213/70 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C07D 413/06 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2073240

2073240 9110652 PCTABS00006 Thioformamide derivatives of formula (I), in which R represents alkyl, Y represents methylene, ethylene or a direct bond, A represents optionally substituted phenyl or heterocyclyl and: R1 represents hydrogen, and R2 represents an N-alkylsulphonyl- or N-phenylsulphonyl-N'-alkylamidino or an aryl- or alkylsulphonyl group; R1 and R2 both independently represents alkyl- or aryl-sulphonyl groups; or R1 and R2 form together with the nitrogen atom a 3,5-dioxomorpholino group or analogue thereof; and salts thereof possess pharmacological activity and are also useful in inhibiting head hair loss.

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