Piperidine derivatives and their use as selective inhibitors...

Details Piperidine derivatives and their use as selective inhibitors... Piperidine derivatives and their use as selective inhibitors...

C - Chemistry, Metallurgy

07

D

C07D 211/46 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2492651

A compound of the formula (I) wherein a, b, c R1, R2, R3, R4, R5, R6, R7, Q, W, Y, and Z are defined as above , useful as potent and selective inhibitors of MIP-1.alpha. (CCL3) binding to its receptor CCR1 found on inflammatory and immunomodulatory cells (preferably leukocytes and lymphocytes).

L'invention concerne un composé représenté par la formule (I) dans laquelle a, b, c R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, Q, W, Y, et Z sont tels que définis dans les spécifications. Ces composés sont utilisés comme inhibiteurs potentiels et sélectifs de la liaison de MIP-1? (CCL3) à son récepteur CCR1 trouvée sur des cellules inflammatoires et immunomodulatrices (de préférence, des leucocytes et des lymphocytes).

Affiliated with

Also associated with

Rating

Piperidine derivatives and their use as selective inhibitors... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Piperidine derivatives and their use as selective inhibitors..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Piperidine derivatives and their use as selective inhibitors... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2020916