Methods of using and compositions comprising pde4 modulators...

A - Human Necessities – 61 – K

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Details

A61K 31/28 (2006.01) A61K 31/335 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2544589

Methods of treating, preventing and managing an asbestos-related disease or disorder are disclosed. Specific embodiments encompass the administration of a PDE4 modulator, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active agent and/or chemotherapy, surgery, or radiation therapy. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in the methods of the invention are also disclosed.

L'invention concerne des méthodes de traitement, de prévention et/ou de gestion d'une maladie ou d'un trouble associé à l'amiante. Des modes de réalisation spécifiques de l'invention consistent à administrer un modulateur de PDE4, ou un sel, ou un solvate, ou un hydrate, ou un stéréoisomère, ou un clathrate, ou un promédicament pharmaceutiquement acceptable de celui-ci, seul, ou combiné à un second principe actif et/ou à une chimiothérapie, à une chirurgie, ou à une radiothérapie. L'invention concerne également des compositions, des formes dosifiées monodoses, et des trousses conçues pour être utilisées dans les méthodes de l'invention.

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