Compounds which can be used to diagnose and monitor diseases...

C - Chemistry – Metallurgy – 07 – D

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C07D 215/30 (2006.01) A61K 51/04 (2006.01) A61P 25/28 (2006.01) C07D 215/28 (2006.01)

Patent

CA 2505506

The invention relates to compounds having general formulae I, II and III, which can be used to diagnose and monitor diseases associated with the deposit of amyloid proteins in the central nervous system. The invention also relates to the use of the inventive compounds in the diagnosis of the aforementioned diseases, to pharmaceutical compositions containing the compounds and to methods of preparing said compounds.

La présente invention concerne des composés représentés par les formules générales (I), (II) et (III) qui sont utiles pour le diagnostic et le suivi de maladies associées au dépôt de protéines amyloïdes dans le système nerveux central. L'invention concerne également l'utilisation de ces composés dans le diagnostic de ces maladies, des compositions pharmaceutiques contenant ces composés, et, enfin, des méthodes destinées à la préparation de ces composés.

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