C20orf23 as modifier of the igfr pathway and methods of use

Details C20orf23 as modifier of the igfr pathway and methods of use C20orf23 as modifier of the igfr pathway and methods of use

G - Physics

01

N

G01N 33/53 (2006.01) A61K 38/00 (2006.01) C07K 1/00 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2559544

Human C20ORF23 genes are identified as modulators of the IGFR pathway and thus are therapeutic targets for disorders associated with defective IGFR function Methods for identifying modulators of IGFR comprising screening for agents that modulate the activity of C20ORF23 are provided.

On a identifié des gênes humains utilisés en tant que modulateurs de la voie IGFR et, par conséquent, en tant que cibles thérapeutiques destinées aux troubles associés à une fonction IGFR déficiente. L'invention concerne aussi des procédés pour identifier les modulateurs d'IGFR comprenant le criblage d'agents qui modulent l'activité des C20ORF23.

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