C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) A61K 38/08 (2006.01) A61K 49/00 (2006.01) C07K 14/47 (2006.01) C12N 9/06 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2673248
This invention relates to novel peptides, discovered by using phage display technique, that bind to VAP-1 (Vascular Adhesion Protein-1). The invention concerns also peptides useful as VAP-1 ligands. Such peptides constitute a portion of natural proteins that are present in the individual. The invention relates particularly to a peptide chain in the leukocyte surface protein, where said peptide chain is useful as a ligand for the VAP-1 molecule and thus facilitates the binding of leukocytes to the vascular endothelium. Furthermore, the invention relates to pharmaceutical and diagnostic compositions for targeting VAP-1 in vivo.
La présente invention concerne de nouveaux peptides, découverts à l'aide d'une technique d'affichage de phages, qui se fixent à la VAP-1 (protéine 1 d'adhésion vasculaire). L'invention concerne également des peptides utiles comme ligands de la VAP-1. Ces peptides constituent une partie de protéines naturelles qui sont présentes chez l'individu. L'invention concerne plus particulièrement une chaîne peptidique dans la protéine de surface des leucocytes, ladite chaîne peptidique étant utile comme ligand pour la molécule VAP-1 et facilitant la fixation de leucocytes sur l'endothélium vasculaire. L'invention concerne également des compositions pharmaceutiques et d'agonistiques permettant de cibler la VAP-1 in vivo.
Elima Kati
Jalkanen Sirpa
Kivi Elina
Faron Ventures Oy
Robic
LandOfFree
Novel peptides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel peptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel peptides will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2023704