Dna encoding phage abortive infection protein from...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/31 (2006.01) A23C 9/123 (2006.01) A23C 19/032 (2006.01) C07K 14/315 (2006.01) C12N 1/21 (2006.01) C12N 15/74 (2006.01)

Patent

CA 2237494

DNA encoding phage resistance protein which aborts infection by the phage, designated as AbiE. The DNA which is contained in a Lactococcus lactis deposited as NRRL-B-21443 and described in SEQ ID NO:1, is incorporated into a bacterium to encode the AbiE and provide phage resistance. Lactococcus and other bacteria encoding the AbiE are useful in industrial fermentations wherein phage are a problem.

L'invention porte sur un ADN codant une protéine de résistance à un phage, dénommée AbiE, cette protéine faisant avorter une infection due au phage. L'ADN, qui se trouve dans un Lactococcus lactis déposé sous la référence NRRL-B-21443 et que décrit la séquence SEQ ID N·:1, est introduit dans une bactérie afin de coder la protéine AbiE et conférer une résistance au phage. La bactérie Lactococcus et d'autres bactéries s'avèrent utiles dans des fermentations industrielles dans lesquelles des phages constituent un problème.

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