Method for inactivation of microorganisms using...

A - Human Necessities – 61 – K

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A61K 35/14 (2006.01) A01N 43/90 (2006.01) A01P 1/00 (2006.01) A61L 2/08 (2006.01) A61L 2/10 (2006.01) A61L 2/16 (2006.01)

Patent

CA 2381594

Methods and apparatuses for treating fluids to inactivate microorganisms which may be present therein, said fluid containing one or more components selected from the group consisting of protein, blood and blood constituents are provided. The methods comprise adjusting the percentage of plasma in said fluid to a desired value; mixing an inactivation-effective, substantially non-toxic amount of an endogenous photosensitizer or endogenously-based derivative photosensitizer to said fluid; exposing said fluid to photoradiation of sufficient wavelength and energy to activate the photosensitizer, whereby said microorganisms are inactivated. Image

L'invention concerne des procédés et appareils de traitement d'un fluide donné pour inactiver des micro-organismes qu'il renferme éventuellement. Ledit fluide contient au moins un composant choisi dans le groupe formé de protéines, de sang et de constituants sanguins. Les procédés consistent à: régler le pourcentage de plasma dans ledit fluide à la valeur voulue; mélanger au fluide une dose d'inactivation efficace, sensiblement non toxique d'un photosensibilisant endogène ou d'un photosensibilisant dérivé à base endogène; exposer le fluide à un photorayonnement de longueur d'onde et d'énergie suffisantes pour activer le photosensibilisant, ce qui permet d'inactiver lesdits micro-organismes.

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