Agent for oral intake, its production and use

Details Agent for oral intake, its production and use Agent for oral intake, its production and use

A - Human Necessities

61

K

A61K 47/42 (2006.01) A23L 1/305 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2245754

The invention relates to an agent for oral intake containing at least one compressed, non-toxic carrier which is at least partially broken down, or can be broken down, or is eliminated or can be eliminated via the digestive tract, whereby the carrier, after expanding in the stomach, has a sponge-like structure, characterized in that the carrier, at least partially, has a collagen structure; it also relates to a process for the production of the agent of the above-mentioned type, wherein a fine-pore sponge consisting of collagen and having a density ranging from 0.005 g/cm3 to 1 g/cm3 - which has optionally been treated with at least one active ingredient and/or additive prior to the pressing procedure, optionally in the presence of a mold-release agent - is compressed to half to one-fiftieth, preferably one-third to one-thirtieth of its original size, and it also relates to the use of this agent and of this process.

L'invention porte sur un agent pour administration orale, renfermant au moins un véhicule non toxique, comprimé, lequel est au moins partiellement ou peut être totalement brisé, ou est ou peut être éliminé dans la voie digestive; après expansion dans l'estomac, le véhicule devient spongieux, avec une structure qui est au moins partiellement celle du collagène; l'invention porte aussi sur une méthode de production du type d'agent susmentionné, où un produit spongieux à pores fins, constitué de collagène, avec une masse spécifique de 0005-1g/cm3 - qui a été traité facultativement avec au moins un ingrédient actif et (ou) un additif avant l'étape de compression, facultativement en présence d'un agent de démoulage - est comprimé à un 1/2-1/50, et préférablement à 1/30, de sa taille initiale; l'invention porte également sur l'utilisation de cet agent et de ce procédé.

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