C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/70 (2006.01) C12N 15/49 (2006.01) C12N 15/57 (2006.01) C12Q 1/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2375905
This invention relates to antiviral drug susceptibility and resistance tests to be used in identifying effective drug regimens for the treatment of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS), particularly treatment regimens including a protease inhibitor. The invention further relates to the means and methods of monitoring the clinical progression of HIV infection and its response to antiretroviral therapy using phenotypic or genotypic susceptibility assays.
Cette invention se rapporte à des épreuves de sensibilité et de résistance à un médicament antiviral pouvant être utilisées pour identifier des régimes posologiques efficaces pour le traitement de l'infection par le virus de l'immunodéficience humaine (VIH) ou du syndrome d'immunodéficience acquise (SIDA), notamment des régimes thérapeutiques comprenant un inhibiteur de la protéase. L'invention se rapporte en outre aux moyens et aux méthodes utilisant des épreuves de sensibilité phénotypiques ou génotypiques pour surveiller l'évolution clinique de l'infection à VIH et la réaction de cette dernière à un traitement antirétroviral.
Parkin Neil T.
Ziermann Rainer A.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Virologic Inc.
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