Predicting heart failure following myocardial infarction by...

G - Physics – 01 – N

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G01N 33/53 (2006.01) C12Q 1/37 (2006.01) G01N 33/543 (2006.01) G01N 33/573 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2657249

Disclosed herein are methods of detecting or predicting diastolic heart failure in a subject, comprising identifying a profile of matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) from a body fluid of the subject that is associated herein with the existence of likely development of left ventricular dilation (LVD).

L'invention concerne des procédés de détection ou de prévision d'une insuffisance cardiaque diastolique chez un sujet, comprenant l'identification d'un profil de métalloprotéinases matricielles (MMP) et d'inhibiteurs tissulaires de métalloprotéinases matricielles (TIMP) dans un fluide corporel du sujet, ledit profil étant associé à l'existence d'un développement probable d'une dilatation ventriculaire gauche (LVD).

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