C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 31/00 (2006.01) A61K 33/00 (2006.01) A61K 38/00 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 1/00 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) C12Q 1/02 (2006.01) C12Q 1/48 (2006.01) C40B 30/04 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2606341
The present invention relates to the selection of a set of polymorphism markers for use in genome wide association studies based on linkage disequilibrium mapping. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's susceptibility to Crohn's disease and/or their response to a particular drug or drugs.
L'invention porte sur la sélection d'un ensemble de marqueurs de polymorphisme utilisables dans des études de larges associations génomiques basées sur une cartographie des déséquilibres des liaisons. L'invention porte en particulier sur les domaines de la pharmacogénomique, du diagnostic, de la thérapie des patients et sur l'utilisation d'haplotypes génétiques pour prédire la susceptibilité d'individus à la maladie de Crohn et/ou leur réponse à une ou des médications particulières.
Allard Rene
Belouchi Abdelmajid
Bradley Walter Edward
Croteau Pascal
Debrus Sophie
Genizon Biosciences Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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