Use of isovaleramide as a mild anxiolytic and mild sedative...

A - Human Necessities – 61 – K

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A61K 31/16 (2006.01)

Patent

CA 2164842

Isovaleramide has been found to exhibit mild anxiolytic (anxiety-reducing) activity at low to moderate dosage levels and mild sedative activity at somewhat higher dosage levels. In contrast to certain other materials thought to be anxiolytic or mildly sedative, isovaleramide is non-cytotoxic and does not paradoxically stimulate the central nervous system. Isovaleramide is therefore useful as a mild anxiolytic and mild sedative agent which can be made available to the general public.

On a découvert que l'isovaléramide présente une activité anxiolytique légère (de réduction de l'anxiété) en doses faibles à modérées, ainsi qu'une activité sédative légère en doses plus élevées. A la différence de certaines autres substances considérées comme étant anxiolytiques ou faiblement sédatives, l'isovaléramide est non-cytotoxique et ne stimule pas paradoxalement le système nerveux central. L'isovaléramide est donc utile en tant qu'anxiolytique léger et agent sédatif léger pouvant être commercialisé auprès du grand public.

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