Automated robotic device for dynamically controlled...

Details Automated robotic device for dynamically controlled... Automated robotic device for dynamically controlled...

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) B01D 9/00 (2006.01) C12M 3/06 (2006.01) C12Q 1/02 (2006.01) C30B 7/00 (2006.01) G01N 1/00 (2006.01) G01N 21/84 (2006.01) G01N 25/14 (2006.01) G01N 35/08 (2006.01)

Patent

CA 2424033

Apparatus and methods are provided for independently controlling dynamic, reagent-induced transformations of multiple samples including proteins being crystallized and cells being cultured. The invention provides an automatic robotic device that enhances protein crystallization in high-throughput, using reagent reservoirs (28) linked to reagent chambers (40), with sample chambers (44) communicating with the reagent chambers (40) via semipermeable membrane.

La présente invention concerne un appareil et des procédés permettant le contrôle indépendant des transformations dynamiques provoquées par des réactifs d'une pluralité d'échantillons comprenant des protéines en cours de cristallisation et des cellules en cours de culture. L'invention propose un dispositif robotique automatique qui améliore la cristallisation des protéines en production élevée, au moyen de réservoirs de réactifs (28) reliés à des enceintes de réactifs (40), avec des chambres d'échantillons (44) communiquant avec les réservoirs de réactifs (28) via une membrane semi-perméable.

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