In vitro model for priocidal activity

G - Physics – 01 – N

Patent

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Details

G01N 33/68 (2006.01) A61K 31/327 (2006.01) A61L 2/00 (2006.01) A61L 2/14 (2006.01) A61L 2/18 (2006.01) A61L 2/20 (2006.01) C11D 3/39 (2006.01) C11D 11/00 (2006.01)

Patent

CA 2462871

A proteinaceous material bas been found to show similar activity and treatment response to that of disease causing prions, such as CJD. A prion model which incorporates the proteinaceous material bas a variety of applications. The model bas an ability to be cultured either in vivo or in vitro, allowing rapid screening of potential drugs for treating animals or humans, or methods of treating food products or items which may come into contact with prions, such as medical or dental devices. Several treatment methods and materials have been developed using the model.

Une matière protéinique a été découverte qui présente une activité et une réponse au traitement similaires à celles de prions pathogènes, tels que ceux qui sont à l'origine de la maladie de Creuzfeldt-Jakob. L'invention concerne un modèle de prion dans lequel est incorporée la matière protéinique précitée, qui possède une variété d'applications. Le modèle de l'invention peut être cultivé in vivo ou in vitro, permettant de la sorte le criblage rapide de médicaments potentiels destinés au traitement d'animaux ou d'humains, ou de procédés de traitement de produits alimentaires ou d'articles susceptibles d'entrer en contact avec des prions, tels que des dispositifs médicaux ou dentaires. Plusieurs procédés et matériels de traitement ont été mis au point à partir du modèle de l'invention.

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