Treatment of abnormalities of the first metatarsophalangeal...

A - Human Necessities – 61 – K

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A61K 38/48 (2006.01) A61P 21/00 (2006.01)

Patent

CA 2555939

Disclosed is a use of a neuromuscular toxin in the preparation of a medicament for the treatment of abnormalities of the first metatarsophalangeal joint of the foot of a mammal. Preferred embodiments include use of toxins capable of interfering with the connection between muscle and nerve, e.g. botulinum toxin, in the preparation of medicaments to treat such abnormalities as hallux abductovalgus, hallux varus, hallux limitus, and hallux rigidus.

L'invention concerne l'utilisation d'une toxine neuromusculaire dans la préparation d'un médicament destiné au traitement des anomalies de la première articulation métatarsophalangienne du pied d'un mammifère. Les modes de réalisation de l'invention comprennent des toxines capables d'interférence dans l'interconnexion entre le muscle et le nerf, tel que la toxine botulinique, qui s'utilise dans des préparations pour traiter des anomalies telles que hallux abductovalgus, hallux varus, hallux limitus ou hallux rigidus.

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