Hyrdroxyamidine derivatives

Details Hyrdroxyamidine derivatives Hyrdroxyamidine derivatives

C - Chemistry, Metallurgy

07

C

C07C 259/18 (2006.01) A61K 31/165 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61K 31/33 (2006.01) C07C 323/47 (2006.01) C07D 207/34 (2006.01) C07D 213/75 (2006.01) C07D 233/88 (2006.01) C07D 295/192 (2006.01) C07D 307/66 (2006.01) C07D 333/36 (2006.01)

Patent

CA 2110838

Hydroxyamidine Derivatives Abstract of the Disclosure The invention relates to the compounds of the formula I Image (I) wherein R1, R2, R3, R4, X1, X2 and X3 are as defined in the specification. The compounds are useful, for example, as selective LTB4 receptor antagonists in the treatment of conditions or syndromes in mammals which are responsive to LTB4 receptor antagonism. They are prepared in a manner known per se.

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