Use of a compound in the treatment of sleep disorders

Details Use of a compound in the treatment of sleep disorders Use of a compound in the treatment of sleep disorders

A - Human Necessities

61

K

A61K 31/4439 (2006.01) A61P 25/26 (2006.01)

Patent

CA 2524805

There is disclosed the use of triprolidine, in combination with at least one further active pharmaceutical agent, for enabling an individual to wake refreshed after sleep and the method of treating such an individual with triprolidine. Use of triprolidine, in combination with at least one further active pharmaceutical agent, as active ingredient in the manufacture of a composition for the treatment of sleep disorders is also described. A method of treating sleep of a person suffering from a sleep disorder, which method comprises administration of an effective dose of triprolidine, in combination with at least one further active pharmaceutical agent, as active ingredient to such a person is also described. The triprolidine is administered shortly before a person wishes to fall asleep, preferably orally and most commonly in the form of a tablet containing up to 20mg, e.g. 0.1mg, 1.25mg or 2.5mg, of the active ingredient. The triprolidine is also effective in enabling an individual to sleep more easily.

L'invention concerne l'utilisation de la triprolidine en association avec au moins un autre agent pharmaceutique actif, pour permettre à un individu de se réveiller frais et dispos après le sommeil, et un procédé de traitement dudit individu avec la triprolidine. L'invention concerne également l'utilisation de la triprolidine comme ingrédient actif, en association avec au moins un autre agent pharmaceutique actif, dans la production d'une composition destinée au traitement de troubles du sommeil. On décrit une méthode de traitement du sommeil chez un individu souffrant d'un trouble du sommeil. Cette méthode consiste à administrer audit individu une dose efficace de triprolidine utilisée comme ingrédient actif, en association avec au moins un autre agent pharmaceutique actif. La triprolidine est administrée peu avant que la personne ne souhaite s'endormir, de préférence par voie orale, et plus communément sous la forme d'un comprimé contenant jusqu'à 20 mg, par exemple 0,1 mg, 1,25 mg ou 2,5 mg de l'ingrédient actif. La triprolidine peut également faciliter le sommeil d'un individu.

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