Methods for detecting mutations using primer extension

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2381625

Methods for detecting nucleotide deletions in biological samples are described. Methods of the invention are particularly useful for detecting deletions in regions of polynucleotide repeats. In particular, methods of the invention are useful to detect deletions at the BAT26 locus.

L'invention concerne des méthodes de détection de délétions nucléotidiques dans des échantillons biologiques. Les méthodes de l'invention sont particulièrement utiles pour détecter des délétions dans des zones de séquences polynucléotidiques répétées. Les méthodes de l'invention sont notamment utiles pour détecter des délétions sur le locus BAT26.

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