Prostacyclin derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 59/46 (2006.01) A61K 31/19 (2006.01) A61K 31/5585 (2006.01) C07D 307/937 (2006.01)

Patent

CA 2672904

This invention relates to novel prostacyclin derivatives, their acceptable acid addition salts, solvates, hydrates and polymorphs thereof. The invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions beneficially treated by prostacyclin, and in particular those diseases and conditions beneficially treated by dilators of systemic and pulmonary arterial vascular beds or by platelet aggregation inhibitors.

La présente invention concerne de nouveaux dérivés de prostacycline, leurs sels d'addition acides, leurs solvates, leurs hydrates et leurs polymorphes de qualité pharmaceutique. L'invention concerne également des compositions comprenant un composé de la présente invention et l'utilisation de ces compositions dans des méthodes destinées au traitement de maladies et de troubles pouvant être traités avec de la prostacycline, en particulier des maladies et des troubles pouvant être traités par des dilatateurs du réseau artériel pulmonaire et systémique ou par des inhibiteurs de l'agrégation plaquettaire.

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